Mitochondrial Metabolism: A New Dimension of Personalized Oncology

Energy is needed by cancer cells to stay alive and communicate with their surroundings. The primary organelles for cellular metabolism energy synthesis are mitochondria. Researchers recently proved that can steal immune cells’ mitochondria using nanoscale tubes. This finding demonstrates the dependence of on normal living function. It also denotes importance in biology. Emerging evidence has demonstrated how essential survive harsh tumor microenvironments, evade system, obtain more aggressive features, resist treatments. For instance, functional improve resistance against radiotherapy scavenging released reactive oxygen species. Therefore, targeting potentially enhance oncological outcomes, according this notion. tumors’ responses anticancer treatments vary, ranging from a complete response even progression during treatment. personalized treatment crucial importance. So far, been based genomic analysis. Evidence shows tumors high mitochondrial content resistant paper illustrates participate chemotherapy, immunotherapy, radiotherapy. Pretreatment evaluation provide additional information analysis help article outlines biology